Article

Endotoxemia and TLR4 via tissue resident macrophages triggers anemia in mouse model of colitis

2026-03-20

Abstract excerpt

Anemia is one of the most debilitating and frequent complications of inflammatory bowel diseases (IBD) and is often treated with iron supplementation, which has limited efficacy. Damaged intestinal barrier function is a hallmark of IBD and causes the translocation of endotoxins from gut bacteria into the bloodstream. In a previous study in mice, we reported that endotoxin suppresses erythropoiesis by reprogramming...

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Literature Corpus work: 98d6f8ea-771c-5691-a566-c3c425c93df3
DOI: 10.64898/2026.03.16.712224

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