Article
Characterization of IIB-MEL-J: a new and highly heterogenous human melanoma cell line.
Pigment cell research - 1 Jan 2000
Guerra L, Mordoh J, Slavutsky I, Larripa I, Medrano E E
Abstract excerpt
A highly heterogeneous cell line, IIB-MEL-J, was established from a human metastatic melanoma. This cell line contains small cells, dendritic cells, and megacells with multiple nuclei. IIB-MEL-J expresses S 100, cytokeratin intermediate filaments and the gangliosides GD2 and GD3. It requires growth factors (insulin, EGF, and transferrin) and antioxidants for optimal growth. When plated under optimal conditions,...
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