Article
Experimental analysis of the metastatic phenotype of malignant leukocytes.
Anticancer research - 1 Jan 2000
Vanden Driessche T, Verschueren H, Verhaegen S, Van Hecke D, De Baetselier P
Abstract excerpt
The metastatic phenotype (M+) is determined by the expression of the invasive (I+) and growth (G+) phenotypes at various sites along the metastatic pathway. The G, I and M phenotypes are not confined to tumor cells and may be expressed by normal cells, such as leukocytes, under certain physiological conditions. The study of the I and M phenotypes of leukocytes may yield valuable information on common mechanisms,...
Topics
- Animals
- Cell Line
- Humans
- Leukocytes
- Lymphocytes
- Mice
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Phenotype