Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of a new human melanoma cell line with CD133 expression.

Human cell - 1 Jun 2012

Gil-Benso Rosario, Monteagudo Carlos, Cerdá-Nicolás Miguel, Callaghan Robert C, Pinto Sandra, Martínez-Romero Alicia, Pellín-Carcelén Ana, San-Miguel Teresa, Cigudosa Juan C, López-Ginés Concha

Abstract excerpt

A novel human malignant melanoma cell line, designated MEL-RC08, was established from a pericranial metastasis of a malignant melanoma of the skin. The cell line has been subcultured for more than 150 passages and is tumorigenic in nude mice. Growth kinetics, cytogenetics, flow cytometry, and molecular techniques for analysis of the genes implicated in cell cycle control; mutations in BRAF, NRAS, C-KiT, RB, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AC133 Antigen
Share to Antigens, CD

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Cycle

Share to Glycoproteins

Share to Melanoma

Share to Neoplastic Stem Cells

Share to Proto-Oncogene Proteins c-kit

Share to Skin Neoplasms

Source

Identifiers

PMID: 22529031
DOI: 10.1007/s13577-011-0027-y

Genes

BRAF
CDK4
MDM2
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of a new human melanoma cell line with CD133 expression.PMID 22529031Read ↗

Cancer stem cells and human malignant melanomaSemantic proximity Read ↗

Stem cells in melanoma development.Semantic proximity Read ↗

Cellular and molecular biology of cancer stem cells in melanoma: Possible therapeutic implicationsSemantic proximity Read ↗

Establishment of a novel Chinese metastatic melanoma cell line showing the new cytogenetic and biological properties.Semantic proximity Read ↗

The Stem Cell-Associated Antigen CD133 (Prominin-1) Is a Molecular Therapeutic Target for Metastatic MelanomaSemantic proximity Read ↗

Establishment and characterization of a cell line (OS-MM) originating from a human malignant melanoma of the oral mucosa.Semantic proximity Read ↗

MDR1 expression identifies human melanoma stem cellsSemantic proximity Read ↗

Therapeutic implications of cellular and molecular biology of cancer stem cells in melanomaSemantic proximity Read ↗

Establishment and molecular characterization of HCB-541, a novel and aggressive human cutaneous squamous cell carcinoma cell line.Semantic proximity Read ↗

Uveal melanoma cell lines contain stem-like cells that self-renew, produce differentiated progeny, and survive chemotherapy.Semantic proximity Read ↗

The Nerve Growth Factor Receptor CD271 Is Crucial to Maintain Tumorigenicity and Stem-Like Properties of Melanoma CellsSemantic proximity Read ↗

A Tumorigenic Subpopulation with Stem Cell Properties in MelanomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.