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Article

Establishment and characterization of a cell line (OS-MM) originating from a human malignant melanoma of the oral mucosa.

In vitro cellular & developmental biology. Animal - 1 May 2026

Shintani Tomoaki, Hamada Atsuko, Yamasaki Sachiko, Jono Yukari, Koizumi Koichi, Tani Ryouji, Sakamoto Akihiko, Kudo Yasusei, Kajiya Mikihito, Yanamoto Souichi, Okamoto Tetsuji

Abstract excerpt

The prognosis for patients diagnosed with oral mucosal melanoma is poor, and the etiology of this disease remains to be elucidated. The underlying reason for this is that no malignant melanoma (MM) cell line derived from oral mucosal tissue has been successfully established to date. The establishment of a human MM cell line designated OS-MM from a tissue sample of a patient diagnosed with palatal mucosal melanoma...

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Identifiers

PMID: 41723313
DOI: 10.1007/s11626-026-01162-2
PMCID: PMC13246917

Genes

BRAF
GNAS
NRAS

Provenance

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