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Article

HIF3A association with adiposity: the story begins before birth.

Epigenomics - 1 Jan 2015

Pan Hong, Lin Xinyi, Wu Yonghui, Chen Li, Teh Ai Ling, Soh Shu E, Lee Yung Seng, Tint Mya Thway, MacIsaac Julia L, Morin Alexander M, Tan Kok Hian, Yap Fabian, Saw Seang Mei, Kobor Michael S, Meaney Michael J, Godfrey Keith M, Chong Yap-Seng, Gluckman Peter D, Karnani Neerja, Holbrook Joanna D

Abstract excerpt

AIM: Determine if the association of HIF3A DNA methylation with weight and adiposity is detectable early in life. MATERIAL & METHODS: We determined HIF3A genotype and DNA methylation patterns (on hybridization arrays) in DNA extracted from umbilical cords of 991 infants. Methylation levels at three CpGs in the HIF3A first intron were related to neonatal and infant anthropometry and to genotype at nearby...

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Identifiers

PMID: 26011824
DOI: 10.2217/epi.15.45
PMCID: PMC4863876

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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