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Article

Early-life determinants of hypoxia-inducible factor 3A gene (HIF3A) methylation: a birth cohort study

1 Jul 2019

Abstract excerpt

BACKGROUND: Methylation of the hypoxia-inducible factor 3α gene (HIF3A) has been linked to pregnancy exposures, infant adiposity and later BMI. Genetic variation influences HIF3A methylation levels and may modify these relationships. However, data in very early life are limited, particularly in association with adverse pregnancy outcomes. We investigated the relationship between maternal and gestational factors,...

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PMID: 31262346
DOI: 10.1186/s13148-019-0687-0

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