Article
DNA methylation patterns in cord blood DNA and body size in childhood.
PloS one - 1 Jan 2012
Relton Caroline L, Groom Alexandra, St Pourcain Beate, Sayers Adrian E, Swan Daniel C, Embleton Nicholas D, Pearce Mark S, Ring Susan M, Northstone Kate, Tobias Jon H, Trakalo Joseph, Ness Andy R, Shaheen Seif O, Davey Smith George
Abstract excerpt
BACKGROUND: Epigenetic markings acquired in early life may have phenotypic consequences later in development through their role in transcriptional regulation with relevance to the developmental origins of diseases including obesity. The goal of this study was to investigate whether DNA methylation levels at birth are associated with body size later in childhood. PRINCIPAL FINDINGS: A study design involving two...
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