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Article

Prospective multicenter cohort study of estrogen and insulin-like growth factor system in BRCA mutation carriers.

Cancer causes & control : CCC - 1 Aug 2015

Kim J, Johnson L, Skrzynia C, Buchanan A, Gracia C, Mersereau J E

Abstract excerpt

PURPOSE: Major clinical characteristics of BRCA1/2-related cancers include association with estrogen and metabolic consequences. We aimed to evaluate serum estradiol (E2) and insulin-like growth factor 1 (IGF-1) levels as a marker of insulin resistance in BRCA1/2 mutation carriers and high-risk, BRCA-negative controls. METHODS: Eligible cancer-free women (age 18-42 with regular menstrual cycles) who had been...

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Source

Identifiers

PMID: 26006218
DOI: 10.1007/s10552-015-0601-9

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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