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Article

BRCA1: An Endocrine and Metabolic Regulator.

Frontiers in endocrinology - 1 Jan 2022

Werner Haim

Abstract excerpt

The breast and ovarian cancer susceptibility gene (BRCA1) is a tumor suppressor whose mutation has been associated with the development of breast, ovarian and, probably, other malignancies at young ages. The BRCA1 gene product participates in multiple biological pathways including the DNA damage response, transcriptional control, cell growth and apoptosis. Inactivating germline mutations of the BRCA1 gene can be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35432218
DOI: 10.3389/fendo.2022.844575
PMCID: PMC9009035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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