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Article

Aberrant activity in retinal degeneration impairs central visual processing and relies on Cx36-containing gap junctions.

Experimental eye research - 1 Sept 2016

Ivanova Elena, Yee Christopher W, Baldoni Robert, Sagdullaev Botir T

Abstract excerpt

In retinal degenerative disease (RD), the diminished light signal from dying photoreceptors has been considered the sole cause of visual impairment. Recent studies show a 10-fold increase in spontaneous activity in the RD network, challenging this paradigm. This aberrant activity forms a new barrier for the light signal, and not only exacerbates the loss of vision, but also may stand in the way of visual...

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Identifiers

PMID: 26005040
DOI: 10.1016/j.exer.2015.05.013
PMCID: PMC4655183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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