Article
Divergent phenotypes of vision and accessory visual function in mice with visual cycle dysfunction (Rpe65 rd12) or retinal degeneration (rd/rd).
Investigative ophthalmology & visual science - 1 Jun 2008
Thompson Stewart, Mullins Robert F, Philp Alisdair R, Stone Edwin M, Mrosovsky N
Abstract excerpt
PURPOSE: Tests of vision for mice remain limited and the visual phenotype of some retinal disorders in mice remain poorly understood. A novel assay of vision was used to determine how the form and extent of retinal disease affects visual phenotype in mice. METHODS: Retinal histology, the suppression of locomotion by light and visual guidance of locomotion, were assessed in mice with progressive photoreceptor...
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