Article
Aberrant synaptic input to retinal ganglion cells varies with morphology in a mouse model of retinal degeneration.
The Journal of comparative neurology - 15 Dec 2014
Yee Christopher W, Toychiev Abduqodir H, Ivanova Elena, Sagdullaev Botir T
Abstract excerpt
Retinal degeneration describes a group of disorders which lead to progressive photoreceptor cell death, resulting in blindness. As this occurs, retinal ganglion cells (RGCs) begin to develop oscillatory physiological activity. Here we studied the morphological and physiological properties of RGCs in rd1 mice, aged 30-60 days, to determine how this aberrant activity correlates with morphology. Patch-clamp...
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