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Article

Comparative intrinsic optical signal imaging of wild-type and mutant mouse retinas.

Optics express - 26 Mar 2012

Zhang Qiu-Xiang, Zhang Youwen, Lu Rong-Wen, Li Yi-Chao, Pittler Steven J, Kraft Timothy W, Yao Xin-Cheng

Abstract excerpt

Functional measurement is important for retinal study and disease diagnosis. Transient intrinsic optical signal (IOS) response, tightly correlated with functional stimulation, has been previously detected in normal retinas. In this paper, comparative IOS imaging of wild-type (WT) and rod-degenerated mutant mouse retinas is reported. Both 2-month and 1-year-old mice were measured. In 2-month-old mutant mice, time...

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Identifiers

PMID: 22453443
DOI: 10.1364/OE.20.007646
PMCID: PMC3387536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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