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Article

Mutations in the glucocerebrosidase gene are common in patients with Parkinson's disease from Eastern Canada.

The International journal of neuroscience - 1 Jan 2016

Han Fabin, Grimes David A, Li Fang, Wang Ting, Yu Zhe, Song Na, Wu Shichao, Racacho Lemuel, Bulman Dennis E

Abstract excerpt

BACKGROUND: Mutations in the β-glucocerebrosidase gene (GBA) have been implicated as a risk factor for Parkinson's disease (PD). However, GBA mutations in PD patients of different ethnic origins were reported to be inconsistent. METHODS: We sequenced all exons of the GBA gene in 225 PD patients and 110 control individuals from Eastern Canada. RESULT: Two novel GBA variants of c.-119 A/G and S(-35)N, five known...

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Identifiers

PMID: 26000814
DOI: 10.3109/00207454.2015.1023436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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