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How Mitochondrial Dynamism Orchestrates Mitophagy

21 May 2015

Abstract excerpt

Mitochondria are highly dynamic, except in adult cardiomyocytes. Yet, the fission and fusion-promoting proteins that mediate mitochondrial dynamism are highly expressed in, and essential to the normal functioning of, hearts. Here, we review accumulating evidence supporting important roles for mitochondrial fission and fusion in cardiac mitochondrial quality control, focusing on the PTEN-induced putative kinase...

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Identifiers

PMID: 25999423
DOI: 10.1161/circresaha.116.306374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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