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Article

Pairwise growth competition assay for determining the replication fitness of human immunodeficiency viruses.

Journal of visualized experiments : JoVE - 4 May 2015

Manocheewa Siriphan, Lanxon-Cookson Erinn C, Liu Yi, Swain J Victor, McClure Jan, Rao Ushnal, Maust Brandon, Deng Wenjie, Sunshine Justine E, Kim Moon, Rolland Morgane, Mullins James I

Abstract excerpt

In vitro fitness assays are essential tools for determining viral replication fitness for viruses such as HIV-1. Various measurements have been used to extrapolate viral replication fitness, ranging from the number of viral particles per infectious unit, growth rate in cell culture, and relative...

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Identifiers

PMID: 25993602
DOI: 10.3791/52610
PMCID: PMC4542137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25993602-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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