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Article

Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation.

PLoS genetics - 1 May 2015

Phadnis Naina, Cipak Lubos, Polakova Silvia, Hyppa Randy W, Cipakova Ingrid, Anrather Dorothea, Karvaiova Lucia, Mechtler Karl, Smith Gerald R, Gregan Juraj

Abstract excerpt

Proper meiotic chromosome segregation, essential for sexual reproduction, requires timely formation and removal of sister chromatid cohesion and crossing-over between homologs. Early in meiosis cohesins hold sisters together and also promote formation of DNA double-strand breaks, obligate precursors to crossovers. Later, cohesin cleavage allows chromosome segregation. We show that in fission yeast redundant...

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Source

Open in PubMed Open full text

Identifiers

PMID: 25993311
DOI: 10.1371/journal.pgen.1005225
PMCID: PMC4439085

Genes

STAG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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