Article
MDM2 (RS769412) G>A Polymorphism in Cigarette Smokers: a Clue for the Susceptibility to Smoking and Lung Cancer Risk.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Ahmad Dilshad, Bakairy Abdul Karieem, Katheri Abdull Malika, Tamimi Waleed
Abstract excerpt
Cigarette smoke contains oxidants and free radicals which are carcinogens that can induce mutations in humans. Single nucleotide polymorphisms (SNPs) are the most frequent genetic alterations found in the human genome. In the present study, we have examined the ability of the murine double minute 2 (Mdm2) (rs769412) A>G polymorphism in cigarette smokers to predict risk of cancers. Our results showed that of...
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