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Article

Progression of behavioural despair in R6/2 and Hdh knock-in mouse models recapitulates depression in Huntington's disease

16 May 2015

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 25986402
DOI: 10.1016/j.bbr.2015.05.010

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Progression of behavioural despair in R6/2 and Hdh knock-in mouse models recapitulates depression in Huntington's diseasePMID 25986402Read ↗

Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease miceSemantic proximity Read ↗

Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6. <i>Htt</i> <sup> <i>Q111/+</i> </sup> model of Huntington’s diseaseSemantic proximity Read ↗

A Tale of Two Maladies? Pathogenesis of Depression with and without the Huntington’s Disease Gene MutationSemantic proximity Read ↗

Hypothalamic expression of huntingtin causes distinct metabolic changes in Huntington's disease mice.Semantic proximity Read ↗

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.Semantic proximity Read ↗

Delayed onset of huntington′s disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptorsSemantic proximity Read ↗

Environmental enrichment slows disease progression in R6/2 Huntington's disease mice.Semantic proximity Read ↗

Cognitive impairments in a mouse model for Huntington’s disease correlate with presymptomatic locomotion and number of CAG repeatsSemantic proximity Read ↗

Differential effects of SNARE-dependent gliotransmission on behavioral phenotypes in a mouse model of Huntington's disease.Semantic proximity Read ↗

Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease miceSemantic proximity Read ↗

Overexpression of heat shock protein 70 in R6/2 Huntington’s disease mice has only modest effects on disease progressionSemantic proximity Read ↗

Molecular and behavioral analysis of the R6/1 Huntington's disease transgenic mouse.Semantic proximity Read ↗

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