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Article

Molecular and behavioral analysis of the R6/1 Huntington's disease transgenic mouse.

Neuroscience - 1 Jan 2003

Naver B, Stub C, Møller M, Fenger K, Hansen A K, Hasholt L, Sørensen S A

Abstract excerpt

Transgenic mice expressing exon 1 of the human Huntington's disease (HD) gene carrying a 115 CAG repeat (line R6/1) are characterized by a neurologic phenotype involving molecular, behavioral and motor disturbances. We have characterized the R6/1 to establish a set of biomarkers, which could be s...

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Source

Identifiers

PMID: 14643771
DOI: 10.1016/j.neuroscience.2003.08.053

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14643771-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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