Article
[Association analysis of SNP-63 and indel-19 variant in the calpain-10 gene with polycystic ovary syndrome in women of reproductive age].
Cirugia y cirujanos - 1 Jan 2000
Flores-Martínez Silvia Esperanza, Castro-Martínez Anna Gabriela, López-Quintero Andrés, García-Zapién Alejandra Guadalupe, Torres-Rodríguez Ruth Noemí, Sánchez-Corona José
Abstract excerpt
BACKGROUND: Polycystic ovary syndrome is a complex and heterogeneous disease involving both reproductive and metabolic problems. It has been suggested a genetic predisposition in the etiology of this syndrome. The identification of calpain-10 gene (CAPN10) as the first candidate gene for type 2 diabetes mellitus, has focused the interest in investigating their possible relation with the polycystic ovary syndrome,...
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