Article
Comment: CAPN10 alleles are associated with polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism - 1 Aug 2002
Gonzalez Alejandro, Abril Eduardo, Roca Alfredo, Aragón Maria José, Figueroa Maria José, Velarde Pilar, Royo José Luis, Real Luis Miguel, Ruiz Agustín
Abstract excerpt
Polycystic ovary syndrome (PCOS) is characterized by chronic anovulation infertility, hyperandrogenemia, and frequently insulin resistance. This study investigated whether polymorphisms in the CAPN10 gene are related with PCOS etiology. The allelic frequencies and genotypes of CAPN10 polymorphisms UCSNP-44, 43, 19, and 63 were determined in 55 well characterized women with polycystic ovaries and 93 unrelated...
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