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Article

A bioassay to measure energy metabolism in mouse colonic crypts, organoids, and sorted stem cells.

American journal of physiology. Gastrointestinal and liver physiology - 1 Jul 2015

Fan Yang-Yi, Davidson Laurie A, Callaway Evelyn S, Wright Gus A, Safe Stephen, Chapkin Robert S

Abstract excerpt

Evidence suggests that targeting cancer cell energy metabolism might be an effective therapeutic approach for selective ablation of malignancies. Using a Seahorse Extracellular Flux Analyzer, we have demonstrated that select environmental agents can alter colonic mitochondrial function by increas...

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Identifiers

PMID: 25977509
DOI: 10.1152/ajpgi.00052.2015
PMCID: PMC4491508

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25977509-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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