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Analysis of Five Gene Sets in Chimpanzees Suggests Decoupling between the Action of Selection on Protein-Coding and on Noncoding Elements.

Genome biology and evolution - 14 May 2015

Santpere Gabriel, Carnero-Montoro Elena, Petit Natalia, Serra François, Hvilsom Christina, Rambla Jordi, Heredia-Genestar Jose Maria, Halligan Daniel L, Dopazo Hernan, Navarro Arcadi, Bosch Elena

Abstract excerpt

We set out to investigate potential differences and similarities between the selective forces acting upon the coding and noncoding regions of five different sets of genes defined according to functional and evolutionary criteria: 1) two reference gene sets presenting accelerated and slow rates of protein evolution (the Complement and Actin pathways); 2) a set of genes with evidence of accelerated evolution in at...

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PMID: 25977458
DOI: 10.1093/gbe/evv082
PMCID: PMC4494068

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