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Article

Superovulation alters global DNA methylation in early mouse embryo development

7 May 2019

Abstract excerpt

Assisted reproductive technologies are known to alter the developmental environment of gametes and early embryos during the most dynamic period of establishing the epigenome. This may result in the introduction of errors during active DNA methylation reprogramming. Controlled ovarian hyperstimulation, or superovulation, is a ubiquitously used intervention which has been demonstrated to alter the methylation of...

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PMID: 31060426
DOI: 10.1080/15592294.2019.1615353

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