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Article

Extreme-Depth Re-sequencing of Mitochondrial DNA Finds No Evidence of Paternal Transmission in Humans.

PLoS genetics - 1 May 2015

Pyle Angela, Hudson Gavin, Wilson Ian J, Coxhead Jonathan, Smertenko Tania, Herbert Mary, Santibanez-Koref Mauro, Chinnery Patrick F

Abstract excerpt

Recent reports have questioned the accepted dogma that mammalian mitochondrial DNA (mtDNA) is strictly maternally inherited. In humans, the argument hinges on detecting a signature of inter-molecular recombination in mtDNA sequences sampled at the population level, inferring a paternal source for...

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Identifiers

PMID: 25973765
DOI: 10.1371/journal.pgen.1005040
PMCID: PMC4431825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25973765-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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