Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Very low-level heteroplasmy mtDNA variations are inherited in humans.

Journal of genetics and genomics = Yi chuan xue bao - 20 Dec 2013

Guo Yan, Li Chung-I, Sheng Quanhu, Winther Jeanette F, Cai Qiuyin, Boice John D, Shyr Yu

Abstract excerpt

Little is known about the inheritance of very low heteroplasmy mitochondria DNA (mtDNA) variations. Even with the development of new next-generation sequencing methods, the practical lower limit of measured heteroplasmy is still about 1% due to the inherent noise level of the sequencing. In this study, we sequenced the mitochondrial genome of 44 individuals using Illumina high-throughput sequencing technology and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Mitochondrial
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Inheritance Patterns

Share to Mothers

Share to Mutation

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 24377867
DOI: 10.1016/j.jgg.2013.10.003
PMCID: PMC4149221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Very low-level heteroplasmy mtDNA variations are inherited in humans.PMID 24377867Read ↗

Presence and transmission of mitochondrial heteroplasmic mutations in human populations of European and African ancestry.Semantic proximity Read ↗

Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease.Semantic proximity Read ↗

The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease.Semantic proximity Read ↗

The inheritance of mitochondrial DNA heteroplasmy: random drift, selection or both?Semantic proximity Read ↗

The mitochondrial DNA genetic bottleneck: inheritance and beyond.Semantic proximity Read ↗

Inheritance of mitochondrial DNA in humans: implications for rare and common diseases.Semantic proximity Read ↗

Nuclear genetic control of mtDNA copy number and heteroplasmy in humansSemantic proximity Read ↗

Mitochondrial DNA sequence variation is largely conserved at birth with rare de novo mutations in neonates.Semantic proximity Read ↗

Recent Advances in Detecting Mitochondrial DNA Heteroplasmic Variations.Semantic proximity Read ↗

Mitochondrial DNA disorders: from pathogenic variants to preventing transmission.Semantic proximity Read ↗

A population phylogenetic view of mitochondrial heteroplasmySemantic proximity Read ↗

Presence and Transmission of Mitochondrial Heteroplasmic Mutations in Human Populations of European and African AncestrySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.