Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer history

7 Mar 2018

Abstract excerpt

BACKGROUND: There is no international consensus up to which age women with a diagnosis of triple-negative breast cancer (TNBC) and no family history of breast or ovarian cancer should be offered genetic testing for germline BRCA1 and BRCA2 (gBRCA) mutations. Here, we explored the association of age at TNBC diagnosis with the prevalence of pathogenic gBRCA mutations in this patient group. METHODS: The study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA gene mutations in cancer
Share to Breast Cancer Treatment Studies
Share to PARP inhibition in cancer therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29514593
DOI: 10.1186/s12885-018-4029-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer historyPMID 29514593Read ↗

Germline BRCA mutation evaluation in a prospective triple-negative breast cancer registry: implications for hereditary breast and/or ovarian cancer syndrome testing.Semantic proximity Read ↗

Prevalence of BRCA1/2 germline mutations in 21 401 families with breast and ovarian cancer.Semantic proximity Read ↗

BRCA detection rate in an Italian cohort of luminal early-onset and triple-negative breast cancer patients without family history: when biology overcomes genealogy.Semantic proximity Read ↗

Prevalence of BRCA1 and BRCA2 germline mutations in patients with triple-negative breast cancer.Semantic proximity Read ↗

Evaluation of BRCA1/2 mutational status among German and Austrian women with triple-negative breast cancer.Semantic proximity Read ↗

Germline BRCA testing in routine clinical practice: a single-center experience.Semantic proximity Read ↗

Prevalence of BRCA mutations among women with triple-negative breast cancer (TNBC) in a genetic counseling cohort.Semantic proximity Read ↗

Germline Mutations in Triple-Negative Breast CancerSemantic proximity Read ↗

Pathology of BRCA1- and BRCA2-associated Breast Cancers: Known and Less Known Connections.Semantic proximity Read ↗

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers.Semantic proximity Read ↗

Epidemiological and clinicopathological characteristics of BRCA-positive and BRCA-negative breast cancer patients in Greece.Semantic proximity Read ↗

Double heterozygous pathogenic variants prevalence in a cohort of patients with hereditary breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.