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Prevalence of <i>BRCA</i> mutations in an unselected population of triple‐negative breast cancer

5 Oct 2011

Abstract excerpt

BACKGROUND: This study assessed BRCA1 and BRCA2 mutation prevalence in an unselected cohort of patients with triple-negative breast cancer (BC). METHODS: One hundred ninety-nine patients were enrolled. Triple negativity was defined as <1% estrogen and progesterone staining by immunohistochemistry and HER-2/neu not overexpressed by fluorescence in situ hybridization. Having given consent, patients had BRCA1 and...

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PMID: 22614657
DOI: 10.1002/cncr.26576

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