Article
Transcriptomic variation between different Chinese hamster ovary cell lines.
Biotechnology letters - 1 Sept 2015
Blas Marjanca, Francky Andrej, Jamnikar Uroš, Gaser Dominik, Baebler Špela, Blejec Andrej, Gruden Kristina
Abstract excerpt
OBJECTIVES: To identify transcription markers that uniquely determine specific Chinese hamster ovary (CHO) cell lines and can be used for the identification of cell lines in the process of biopharmaceutical cell-line development. RESULTS: Five CHO cell lines with different origins were extensively characterised at the transcriptomic level and the results were compared to their karyotype characterisation. The...
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