Article
Association of the C677T polymorphism in the methylenetetrahydrofolate reductase gene with breast cancer in a Mexican population.
Genetics and molecular research : GMR - 27 Apr 2015
Ramos-Silva A, Figuera L E, Soto-Quintana O M, Puebla-Pérez A M, Ramírez-Patiño R, Gutiérrez-Hurtado I, Carrillo-Moreno D I, Zúñiga-González G M, Dávalos-Rodríguez I P, Gallegos-Arreola M P
Abstract excerpt
The methylenetetrahydrofolate reductase (MTHFR) gene plays an important role in the steps involved in the processing of amino acids. The analysis of polymorphisms in the MTHFR gene has revealed associations with cancer; in particular the C677T polymorphism, which has been suggested to affect fola...
Topics
- Adult
- Breast Neoplasms
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Methylenetetrahydrofolate Reductase (NADPH2)
- Mexico
- Middle Aged
- Odds Ratio
- Polymorphism, Single Nucleotide