Clinical, autoimmune, and genetic characteristics of adult-onset diabetic patients with GAD autoantibodies in Japan (Ehime Study).

doi:10.2337/diacare.25.6.995

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Clinical, autoimmune, and genetic characteristics of adult-onset diabetic patients with GAD autoantibodies in Japan (Ehime Study).

Diabetes care - 1 Jun 2002

Takeda Haruyo, Kawasaki Eiji, Shimizu Ikki, Konoue Etsushi, Fujiyama Masao, Murao Satoshi, Tanaka Kiyonobu, Mori Kennichi, Tarumi Yoshinao, Seto Isamu, Fujii Yasuhisa, Kato Kenichi, Kondo Shiori, Takada Yasuharu, Kitsuki Nobuaki, Kaino Yukikazu, Kida Kaichi, Hashimoto Naotake, Yamane Yukio, Yamawaki Takashi, Onuma Hiroshi, Nishimiya Tatsuya, Osawa Haruhiko, Saito Yasushi, Makino Hideichi

Abstract excerpt

OBJECTIVE: To characterize the clinical, autoimmune, and genetic features in Japanese adult-onset diabetic patients with GAD autoantibodies. RESEARCH DESIGN AND METHODS: GAD autoantibodies (GADab) were screened in 4,980 diabetic patients with age of onset >20 years in the hospital-based Ehime Study, and the GADab-positive (GADab(+)) patients were then divided into two groups according to their insulin secretion...

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PMID: 12032105
DOI: 10.2337/diacare.25.6.995

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