Article
Analyses of EGF A61G Gene Variation and Serum EGF Level on Gastric Cancer Susceptibility and Clinicopathological Parameters.
Anticancer research - 1 May 2015
Cacina Canan, Arikan Soykan, Düzköylü Yigit, Doğan Mehmet Baki, Okay Erdem, Turan Saime, Yaylim Ilhan, Isbir Turgay
Abstract excerpt
BACKGROUND: Epidermal growth factor (EGF) induces various biological signaling pathways, including proliferation and differentiation and it is the natural ligand of the epidermal growth factor receptor (EGFR) which is a member of tyrosine kinase transmembrane receptor family. EGF and EGFR control important processes in carcinogenesis and several differences in this signaling pathway are very common in certain...
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