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Article

Association between epidermal growth factor polymorphism and esophageal squamous cell carcinoma susceptibility.

Digestive diseases and sciences - 1 Jan 2010

Cui Lin, Pan Xin-Min, Ma Chun-Fen, Shang-Guan Jun, Yu Hai-Bin, Chen Guang-Xue, Wang Jia

Abstract excerpt

Genetic factors are known to be important in the development of esophageal squamous cell carcinoma (ESCC). Epidermal growth factor (EGF) can activate several signaling pathways leading to proliferation, differentiation, and tumorigenesis of epithelial tissues by binding with its receptor. Interindividual variations in EGF production were genetically contributed to EGF +61 G/A polymorphism. The purpose of this...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19172394
DOI: 10.1007/s10620-008-0700-5

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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