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Article

The Role of ARF6 in Biliary Atresia.

PloS one - 1 Jan 2015

Ningappa Mylarappa, So Juhoon, Glessner Joseph, Ashokkumar Chethan, Ranganathan Sarangarajan, Min Jun, Higgs Brandon W, Sun Qing, Haberman Kimberly, Schmitt Lori, Vilarinho Silvia, Mistry Pramod K, Vockley Gerard, Dhawan Anil, Gittes George K, Hakonarson Hakon, Jaffe Ronald, Subramaniam Shankar, Shin Donghun, Sindhi Rakesh

Abstract excerpt

BACKGROUND & AIMS: Altered extrahepatic bile ducts, gut, and cardiovascular anomalies constitute the variable phenotype of biliary atresia (BA). METHODS: To identify potential susceptibility loci, Caucasian children, normal (controls) and with BA (cases) at two US centers were compared at >550000 SNP loci. Systems biology analysis was carried out on the data. In order to validate a key gene identified in the...

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Identifiers

PMID: 26379158
DOI: 10.1371/journal.pone.0138381
PMCID: PMC4574480

Genes

ARF6
EGFR
EGF
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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