Article
Dynamic phenotypes of degenerative myxomatous mitral valve disease: quantitative 3-dimensional echocardiographic study.
Circulation. Cardiovascular imaging - 1 May 2015
Clavel Marie-Annick, Mantovani Francesca, Malouf Joseph, Michelena Hector I, Vatury Ori, Jain Mothilal Sonia, Mankad Sunil V, Suri Rakesh M, Enriquez-Sarano Maurice
Abstract excerpt
BACKGROUND: Fibro-elastic deficiency (FED) and diffuse myxomatous degeneration (DMD) are phenotypes of degenerative mitral valve disease defined morphologically. Whether physiological differences in annular and valvular dynamics exist between these phenotypes remains unknown. METHODS AND RESULTS: We performed triple quantitation of cardiac remodeling and of mitral regurgitation severity and of annular and...
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