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Article

Pathophysiology of Degenerative Mitral Regurgitation: New 3-Dimensional Imaging Insights.

Circulation. Cardiovascular imaging - 1 Jan 2018

Antoine Clemence, Mantovani Francesca, Benfari Giovanni, Mankad Sunil V, Maalouf Joseph F, Michelena Hector I, Enriquez-Sarano Maurice

Abstract excerpt

Despite its high prevalence, little is known about mechanisms of mitral regurgitation in degenerative mitral valve disease apart from the leaflet prolapse itself. Mitral valve is a complex structure, including mitral annulus, mitral leaflets, papillary muscles, chords, and left ventricular walls. All these structures are involved in physiological and pathological functioning of this valvuloventricular complex but...

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PMID: 29321211
DOI: 10.1161/CIRCIMAGING.116.005971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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