Article
IKZF1 alterations and expression of CRLF2 predict prognosis in adult Chinese patients with B-cell precursor acute lymphoblastic leukemia.
Leukemia & lymphoma - 1 Jan 2017
Fang Qiuyun, Zhao Xingli, Li Qinghua, Li Yan, Liu Kaiqi, Tang Kejing, Wang Ying, Liu Bingcheng, Wang Min, Xing Haiyan, Rao Qing, Tian Zheng, Wang Jianxiang, Mi Yingchang
Abstract excerpt
Acute Lymphoblastic Leukemia (ALL) is a common hematological malignancy in children, with a prognosis much worse in adults. The molecular characterization of ALL and its correlated prognostic significance are largely unknown. In this study, we analyzed the frequency of IKZF1 deletions, IK6 isoform, and CRLF2 overexpression in 118 Chinese adult B-cell precursor ALL (B-ALL) patients to explore their associations...
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