Article
Evolutionary Diagnosis of non-synonymous variants involved in differential drug response.
BMC medical genomics - 1 Jan 2015
Gerek Nevin Z, Liu Li, Gerold Kristyn, Biparva Pegah, Thomas Eric D, Kumar Sudhir
Abstract excerpt
BACKGROUND: Many pharmaceutical drugs are known to be ineffective or have negative side effects in a substantial proportion of patients. Genomic advances are revealing that some non-synonymous single nucleotide variants (nsSNVs) may cause differences in drug efficacy and side effects. Therefore,...
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