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Article

Evolutionary Diagnosis of non-synonymous variants involved in differential drug response.

BMC medical genomics - 1 Jan 2015

Gerek Nevin Z, Liu Li, Gerold Kristyn, Biparva Pegah, Thomas Eric D, Kumar Sudhir

Abstract excerpt

BACKGROUND: Many pharmaceutical drugs are known to be ineffective or have negative side effects in a substantial proportion of patients. Genomic advances are revealing that some non-synonymous single nucleotide variants (nsSNVs) may cause differences in drug efficacy and side effects. Therefore, it is desirable to evaluate nsSNVs of interest in their ability to modulate the drug response. RESULTS: We found that...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 25952014
DOI: 10.1186/1755-8794-8-S1-S6
PMCID: PMC4315320

Genes

TNR
TPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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