Article
A single nucleotide polymorphism of interleukin-6 gene is related to plasma adrenomedullin levels.
Clinical endocrinology - 1 Oct 2013
Wong Hoi Kin, Ong Kwok Leung, Leung Raymond Y H, Lam Tai Hing, Thomas Graham Neil, Lam Karen S L, Cheung Bernard M Y
Abstract excerpt
OBJECTIVE: Elevated plasma adrenomedullin (ADM) levels are associated with cardiovascular diseases. Single nucleotide polymorphisms (SNPs) in the gene encoding ADM (ADM) are associated with plasma ADM levels. The presence of a nuclear factor for interleukin-6 (IL-6) expression binding site in the promoter region of the ADM gene suggests a possible relationship between the expression of the ADM and IL-6....
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