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Article

Disruption of the lamin A and matrin-3 interaction by myopathic LMNA mutations.

Human molecular genetics - 1 Aug 2015

Depreux Frederic F, Puckelwartz Megan J, Augustynowicz Aleksandra, Wolfgeher Don, Labno Christine M, Pierre-Louis Dynora, Cicka Danielle, Kron Stephen J, Holaska James, McNally Elizabeth M

Abstract excerpt

The nuclear face of the nuclear membrane is enriched with the intermediate filament protein lamin A. Mutations in LMNA, the gene encoding lamin A, lead to a diverse set of inherited conditions including myopathies that affect both the heart and skeletal muscle. To gain insight about lamin A prote...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25948554
DOI: 10.1093/hmg/ddv160
PMCID: PMC4492393

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25948554-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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