Laminopathies and lamin-associated signaling pathways.

Abstract excerpt

Laminopathies are genetic diseases due to mutations or altered post-translational processing of nuclear envelope/lamina proteins. The majority of laminopathies are caused by mutations in the LMNA gene, encoding lamin A/C, but manifest as diverse pathologies including muscular dystrophy, lipodystrophy, neuropathy, and progeroid syndromes. Lamin-binding proteins implicated in laminopathies include lamin B2, nuclear...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Disease
• Share to Lamin Type A
• Share to Lamin Type B