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Article

Identification of differential protein interactors of lamin A and progerin.

Nucleus (Austin, Tex.) - 1 Jan 2000

Kubben Nard, Voncken Jan Willem, Demmers Jeroen, Calis Chantal, van Almen Geert, Pinto Yigal, Misteli Tom

Abstract excerpt

The nuclear lamina is an interconnected meshwork of intermediate filament proteins underlying the nuclear envelope. The lamina is an important regulator of nuclear structural integrity as well as nuclear processes, including transcription, DNA replication and chromatin remodeling. The major components of the lamina are A- and B-type lamins. Mutations in lamins impair lamina functions and cause a set of highly...

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Identifiers

PMID: 21327095
DOI: 10.4161/nucl.1.6.13512
PMCID: PMC3027055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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