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Article

Central role of gimap5 in maintaining peripheral tolerance and T cell homeostasis in the gut.

Mediators of inflammation - 1 Jan 2015

Endale Mehari, Aksoylar H Ibrahim, Hoebe Kasper

Abstract excerpt

Inflammatory bowel disease (IBD) including Crohn's disease and ulcerative colitis is often precipitated by an abnormal immune response to microbiota due to host genetic aberrancies. Recent studies highlight the importance of the host genome and microflora interactions in the pathogenesis of mucosal inflammation including IBD. Specifically, genome-wide (GWAS) and also next-generation sequencing (NGS)-including...

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Identifiers

PMID: 25944983
DOI: 10.1155/2015/436017
PMCID: PMC4405212

Genes

GIMAP5

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