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Article

Genetics and pathogenesis of inflammatory bowel disease.

Nature - 15 Jun 2011

Khor Bernard, Gardet Agnès, Xavier Ramnik J

Abstract excerpt

Recent advances have provided substantial insight into the maintenance of mucosal immunity and the pathogenesis of inflammatory bowel disease. Cellular programs responsible for intestinal homeostasis use diverse intracellular and intercellular networks to promote immune tolerance, inflammation or epithelial restitution. Complex interfaces integrate local host and microbial signals to activate appropriate effector...

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Identifiers

PMID: 21677747
DOI: 10.1038/nature10209
PMCID: PMC3204665

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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