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Article

Expression of thrombospondin-1 by tumor cells in patient-derived ovarian carcinoma xenografts.

Connective tissue research - 1 Jan 2015

Pinessi Denise, Ostano Paola, Borsotti Patrizia, Bello Ezia, Guffanti Federica, Bizzaro Francesca, Frapolli Roberta, Bani Maria Rosa, Chiorino Giovanna, Taraboletti Giulia, Resovi Andrea

Abstract excerpt

PURPOSE: Thrombospondin-1 (TSP-1), a major regulator of cell interaction with the environment, is often deregulated in cancers, including ovarian carcinoma. Both the tumor and the host cells can release TSP-1 in the tumor microenvironment. The relative contribution of the two sources in determining TSP-1 levels in ovarian cancer remains to be elucidated. This study was designed to investigate the expression of...

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Identifiers

PMID: 25943461
DOI: 10.3109/03008207.2015.1045065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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