Back to search

Article

A novel thrombospondin-1 transcript exhibits distinctive expression and activity in thyroid tumorigenesis

2022-11-01

Abstract excerpt

<title>Abstract</title> <p>Thrombospondin 1 (TSP1) is known for its cell-specific functions in cancer progression, such as proliferation and migration. It contains 22 exons that may potentially produce several different transcripts. Here, we identified TSP1V as a novel TSP1 splicing variant produced by intron retention (IR) in human thyroid cancer cells and tissues. We observed TSP1V functionally inhibited tumori...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
262668fe-fa68-52d9-b545-e031edc3daee
DOI
10.21203/rs.3.rs-2156656/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A novel thrombospondin-1 transcript exhibits distinctive expression and activity in thyroid tumorigenesisDOI 10.21203/rs.3.rs-2156656/v1
Tspan protein family: focusing on the occurrence, progression, and treatment of cancerSemantic proximity
Expression and function of transmembrane 4 superfamily proteins in digestive system cancersSemantic proximity
Human expression patterns: qualitative and quantitative analysis of thrombospondin‐1 under physiological and pathological conditionsSemantic proximity
Expression and function of transmembrane 4 superfamily proteins in digestive system cancersSemantic proximity
Molecular Regulation and Oncogenic Functions of TSPAN8Semantic proximity
Assessing CD36 and CD47 expression levels in solid tumor indications to stratify patients for VT1021 treatmentSemantic proximity
Thrombospondins: structure and regulation of expressionSemantic proximity
Thrombospondins as Anti-Angiogenic Therapeutic AgentsSemantic proximity
The role of tetraspanins pan-cancerSemantic proximity
Thrombospondin-2 Holds Prognostic Values and is Associated with the Metastasis and Mismatch Repair Process in Gastric CancerSemantic proximity
The role of thrombospondin‐1 in tumor progression and angiogenesisSemantic proximity
Tspan2: a tetraspanin protein involved in oligodendrogenesis and cancer metastasisSemantic proximity
Select a neighboring publication to make it the new centre.