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Article

Next Generation Sequencing-based analysis of RNA polymerase functions.

Methods (San Diego, Calif.) - 15 Sept 2015

Heyduk Tomasz, Heyduk Ewa

Abstract excerpt

Next Generation Sequencing (NGS) that revolutionized genome wide studies allows analysis of complex nucleic acids mixtures containing thousands of sequences. This extraordinary analytical power of NGS can be harnessed for the analysis of in vitro experiments where DNA template sequence dependence of protein activity acting on DNA can be studied in a single reaction for thousands of DNA sequence variants. This...

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Share to DNA
Share to DNA-Directed RNA Polymerases
Share to Genome, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Protein Biosynthesis

Share to Transcription, Genetic

Source

Identifiers

PMID: 25937393
DOI: 10.1016/j.ymeth.2015.04.030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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