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Article

Correlation of Merkel cell polyomavirus positivity with PDGFRα mutations and survivin expression in Merkel cell carcinoma.

Journal of dermatological science - 1 Jul 2015

Batinica M, Akgül B, Silling S, Mauch C, Zigrino P

Abstract excerpt

BACKGROUND: Merkel cell carcinoma (MCC) is a neuroendocrine cancer of the skin postulated to originate through Merkel cell polyomavirus (MCPyV) oncogenesis and/or by mutations in molecules implicated in the regulation of cell growth and survival. Despite the fact that MCPvV is detected more broadly within the population, only a part of the infected people also develop MCC. It is thus conceivable that together,...

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Share to Carcinoma, Merkel Cell
Share to Genes, p53
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptor, Platelet-Derived Growth Factor alpha

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Identifiers

PMID: 25936870
DOI: 10.1016/j.jdermsci.2015.04.002

Genes

MCC

Provenance

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